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Squamous cell carcinoma is common in children with xeroderma pigmentosum, who are unable to repair DNA damage caused by ultraviolet irradiation. In most persons this inability is due to the deficiency of an endonuclease enzyme. Incomplete repair of damaged DNA causes mutations that appear as basal or squamous cell carcinomas, malignant melanomas, and keratoacanthomas.In adults, squamous cell carcinoma rarely occurs in the absence of an external cause. Protracted exposure to sunlight is the usual cause, but chronic scarring from burns, as well as reactions to vaccinations, radiation dermatitis, and chronic ulceration, may contribute to some cases. Squamous cell carcinoma is also an occupational hazard, as was noted at the end of the 19th century in regard to chimney sweeps who contracted cancer after exposure to tars. Tar-induced squamous cell carcinoma occurs today in workers who distill tar vapour in the manufacture of coal gas and in machinery operators whose clothes and skin become soaked in mineral oil.Because of the high rate of metastasis of squamous cell carcinomas, early diagnosis is important, especially in persons with a skin ulcer that fails to heal. Skin lesions that precede squamous cell carcinoma include white patches in the mucous membranes of the mouth, genitalia, or anus; warty lesions called keratoses (which are especially common after chronic exposure to the Sun, when they are called solar keratoses); and the lesions of Bowen's disease--persistent red scaly plaques that on microscopic examination are found to contain grossly abnormal keratinocytes. When squamous cell carcinoma follows Bowen's disease, there is often a history of treatment with an inorganic arsenical drug.
In Western countries, the mortality from the skin cancer malignant melanoma is increasing by about 4 percent per year. This type of skin cancer arises from the melanocytes of the skin, and the tumor is therefore often, but not invariably, pigmented with melanin. In adults malignant melanoma arises as a new lesion or as a change in a benign pigmented mole. Malignant melanoma metastasizes frequently, and excision of the tumor together with a collar of surrounding healthy skin is curative if done early [statement by conventional mainstream oncology, compare On Conventional Cancer Treatment].
Primary cancers arising in the dermis are much less common than epidermal malignant tumors. Mycosis fungoides is a malignant tumor of the T lymphocytes of the dermis. Despite the name, fungal infection does not cause the cancer.
Extrinsic causes of dermal cancers are rare. An exception is the malignant cutaneous vascular tumor called Kaposi's sarcoma.
Kaposi's sarcoma, also called IDIOPATHIC MULTIPLE PIGMENTED HEMORRHAGIC SARCOMA, is a rare cancer characterized by red-purple or blue-brown macules, plaques, and nodules of the skin
and other organs. The skin lesions may be firm or compressible, solitary or legion.The disease was reported in 1872 by Moritz Kaposi. Before its appearance in those afflicted with acquired immune
deficiency syndrome (AIDS), Kaposi's sarcoma was considered an extremely rare cancer. It was noted primarily among men of Mediterranean descent but had also been observed in an endemic
form among African men. A unique form of Kaposi's sarcoma--with internal (especially lymphatic) rather than cutaneous involvement--had also been recognized among young children in
certain areas of equatorial Africa. The lack of health statistics in Africa seriously hampered efforts to study the history of the disease there, and the reason or reasons for the variation in forms of the
cancer remain unclear. Since about 1980 Kaposi's sarcoma has become increasingly evident in AIDS victims. Of the groups that have been identified as high-risk for AIDS, male homosexuals are far
more likely to develop the cancer than are other AIDS victims. Kaposi's sarcoma, in fact, was the disease that indicated the presence of AIDS in nearly half of the U.S. cases of AIDS that were reported
to the Centers for Disease Control in Atlanta, Ga. The breakdown of the immune system and the production of a growth factor by white blood cells infected with the AIDS virus seem to encourage the
sarcoma's occurrence--i.e., it is considered an opportunistic tumor. There is no known cure for Kaposi's sarcoma, although partial and complete remissions have been accomplished.
Compare Ozone, particularly Do Not Be Deceived! Aids & Cancer are Curable!, Interesting Medical Ozone Facts (Aids, cancer & other illness) and Private Initiative Reports Remissions of Cancer, Aids and Other Ailments Thanks to Budwig Diet & Protocol.
For a larger view of the question of sunlight exposure and skin and other cancers
incl. detailed discussions of the impact of artificial lighting and sunscreens as well as the sun’s crucial role in healing and preventing cancer, compare Healing Cancer With Light, particularly Sunlight, Skin Cancers and Vitamin D and Skin Cancer, Malignant
Melanoma & Sunlight. Also see Oil of cloves and skin cancer.
For the main subject of this site, the holistic healing of cancer, refer to Healing Cancer Naturally & any of the menu points listed at the bottom and top of each page.
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